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Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice
BACKGROUND: Asthma is associated with airway hyperresponsiveness and enhanced T-cell number/activity on one hand and increased levels of exhaled nitric oxide (NO) with expression of inducible NO synthase (iNOS) on the other hand. These findings are in paradox, as NO also relaxes airway smooth muscle...
Autores principales: | Broeke, Robert Ten, De Crom, Rini, Van Haperen, Rien, Verweij, Vivienne, Leusink-Muis, Thea, Van Ark, Ingrid, De Clerck, Fred, Nijkamp, Frans P, Folkerts, Gert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456969/ https://www.ncbi.nlm.nih.gov/pubmed/16597326 http://dx.doi.org/10.1186/1465-9921-7-58 |
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