Functional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226

BACKGROUND: Glycogen Synthase Kinase-3 (GSK3) activity is repressed following insulin treatment of cells. Pharmacological inhibition of GSK3 mimics the effect of insulin on Phosphoenolpyruvate Carboxykinase (PEPCK), Glucose-6 Phosphatase (G6Pase) and IGF binding protein-1 (IGFBP1) gene expression. C...

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Detalles Bibliográficos
Autores principales: Liu, H-K, Perrier, S, Lipina, C, Finlay, D, McLauchlan, H, Hastie, CJ, Hundal, HS, Sutherland, C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456981/
https://www.ncbi.nlm.nih.gov/pubmed/16600022
http://dx.doi.org/10.1186/1471-2199-7-14

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