A novel DNA damage recognition protein in Schizosaccharomyces pombe

Toxic and mutagenic O(6)-alkylguanine adducts in DNA are repaired by O(6)-alkylguanine-DNA alkyltransferases (MGMT) by transfer of the alkyl group to a cysteine residue in the active site. Comparisons in silico of prokaryotes and lower eukaryotes reveal the presence of a group of proteins [alkyltran...

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Detalles Bibliográficos
Autores principales: Pearson, Steven J., Wharton, Stephen, Watson, Amanda J., Begum, Ghazala, Butt, Amna, Glynn, Nicola, Williams, David M., Shibata, Takayuki, Santibáñez-Koref, Mauro F., Margison, Geoffrey P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458281/
https://www.ncbi.nlm.nih.gov/pubmed/16679453
http://dx.doi.org/10.1093/nar/gkl270

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