Cargando…

Small molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells

BACKGROUND: Several small receptor tyrosine kinase inhibitors (RTKI) have entered clinical cancer trials alone and in combination with radiotherapy or chemotherapy. The inhibitory spectrum of these compounds is often not restricted to a single target. For example Imatinib/Gleevec (primarily a bcr/ab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Minglun, Ping, Gong, Plathow, Christian, Trinh, Thuy, Lipson, Kenneth E, Hauser, Kai, Krempien, Robert, Debus, Juergen, Abdollahi, Amir, Huber, Peter E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458351/ https://www.ncbi.nlm.nih.gov/pubmed/16556328 http://dx.doi.org/10.1186/1471-2407-6-79

Ejemplares similares

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
por: Abdollahi, Amir, et al.
Publicado: (2005)

Cetuximab, gemcitabine and radiotherapy in locally advanced pancreatic cancer: Long-term results of the randomized controlled phase II PARC trial
por: Liermann, Jakob, et al.
Publicado: (2022)

Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model
por: Li, Minglun, et al.
Publicado: (2009)

Tyrosine kinase inhibitor SU6668 represses chondrosarcoma growth via antiangiogenesis in vivo
por: Klenke, Frank M, et al.
Publicado: (2007)

Intraoperative Electron Radiation Therapy (IOERT) in the management of locally recurrent rectal cancer
por: Roeder, Falk, et al.
Publicado: (2012)

Aggressive local treatment containing intraoperative radiation therapy (IORT) for patients with isolated local recurrences of pancreatic cancer: a retrospective analysis
por: Roeder, Falk, et al.
Publicado: (2012)

modelBuildR: an R package for model building and feature selection with erroneous classifications
por: Knoll, Maximilian, et al.
Publicado: (2021)

Randomized phase II – study evaluating EGFR targeting therapy with Cetuximab in combination with radiotherapy and chemotherapy for patients with locally advanced pancreatic cancer – PARC: study protocol [ISRCTN56652283]
por: Krempien, R, et al.
Publicado: (2005)

Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC
por: Dai, Ying, et al.
Publicado: (2018)

Effects of platelet-rich plasma on human gingival fibroblast proliferation and migration in vitro
por: NGUYEN, Phuc Anh, et al.
Publicado: (2018)

A Clinical phase I/II trial to investigate preoperative dose-escalated intensity-modulated radiation therapy (IMRT) and intraoperative radiation therapy (IORT) in patients with retroperitoneal soft tissue sarcoma
por: Roeder, Falk, et al.
Publicado: (2012)

Clinical Phase I/II trial to Investigate Preoperative Dose-Escalated Intensity-Modulated Radiation Therapy (IMRT) and Intraoperative Radiation Therapy (IORT) in patients with retroperitoneal soft tissue sarcoma: interim analysis
por: Roeder, Falk, et al.
Publicado: (2014)

Imaging tumour motion for radiotherapy planning using MRI
por: Kauczor, Hans-Ulrich, et al.
Publicado: (2006)

Differential response of esophageal cancer cells to particle irradiation
por: Hartfiel, Sarah, et al.
Publicado: (2019)

Evolution of a Paradigm Switch in Diagnosis and Treatment of HPV-Driven Head and Neck Cancer—Striking the Balance Between Toxicity and Cure
por: Tawk, Bouchra, et al.
Publicado: (2022)

Peptide-Based Targeting of the Platelet-Derived Growth Factor Receptor Beta
por: Askoxylakis, Vasileios, et al.
Publicado: (2012)

Regulation of Fibroblast Cell Polarity by Src Tyrosine Kinase
por: Katoh, Kazuo
Publicado: (2021)

Inhibition of tyrosine kinase receptors by SU6668 promotes abnormal stromal development at the periphery of carcinomas
por: Farace, P, et al.
Publicado: (2009)

Manipulating Tyrosine Phosphorylation by Heterobifunctional Small Molecules
por: Meng, Xianke, et al.
Publicado: (2023)

Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins
Publicado: (1990)

Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions
Publicado: (1995)

Human mesenchymal stem cells lose their functional properties after paclitaxel treatment
por: Münz, Franziska, et al.
Publicado: (2018)

Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment
por: Tullemans, Bibian M. E., et al.
Publicado: (2021)

c‐Cbl Is Inducibly Tyrosine‐phosphorylated by Epidermal Growth Factor Stimulation in Fibroblasts, and Constitutively Tyrosine‐phosphorylated and Associated with v‐Src in v‐src‐transformed Fibroblasts
por: Odai, Hideharu, et al.
Publicado: (1995)

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase
por: Mattila, Elina, et al.
Publicado: (2010)

Binding and degradation of platelet thrombospondin by cultured fibroblasts
Publicado: (1984)

Platelet-derived growth factor in chemotactic for fibroblasts
Publicado: (1982)

Platelet-Poor Plasma as a Supplement for Fibroblasts Cultured in Platelet-Rich Fibrin
por: Chisini, Luiz Alexandre, et al.
Publicado: (2017)

Small molecule tyrosine kinase inhibitors in pancreatic cancer
por: Gupta, Sachin, et al.
Publicado: (2008)

Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin
por: Nicolay, Nils H., et al.
Publicado: (2016)

Mesenchymal stem cells are sensitive to bleomycin treatment
por: Nicolay, Nils H., et al.
Publicado: (2016)

Small Molecules Enable Neurogenin 2 to Efficiently Convert Human Fibroblasts to Cholinergic Neurons
por: Liu, Meng-Lu, et al.
Publicado: (2013)

Human mesenchymal stem cells are resistant to UV-B irradiation
por: Lopez Perez, Ramon, et al.
Publicado: (2019)

Tyrosine kinase signalling in breast cancer: Fibroblast growth factors and their receptors
por: Dickson, Clive, et al.
Publicado: (2000)

Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients
por: Tullemans, Bibian M. E., et al.
Publicado: (2018)

Chemotactic activity of platelet alpha granule proteins for fibroblasts
Publicado: (1983)

Platelets stimulate fibroblast-mediated contraction of collagen gels
por: Zagai, Ulrika, et al.
Publicado: (2003)

Intraoperative radiation therapy (IORT) in soft-tissue sarcoma
por: Roeder, Falk, et al.
Publicado: (2017)

Intraoperative radiation therapy (IORT) in pancreatic cancer
por: Krempien, Robert, et al.
Publicado: (2017)

Feasibility and robustness of dynamic (18)F-FET PET based tracer kinetic models applied to patients with recurrent high-grade glioma prior to carbon ion irradiation
por: Debus, Charlotte, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_oinab88ad0gfmvdv1mgbmfhdqt