Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia

BACKGROUND: Adeno-associated virus type 2 (AAV-2) attachment and internalization is thought to be mediated by host cell membrane-associated heparan sulfate proteoglycans (HSPG). Lack of HSPG on the apical membrane of respiratory epithelial cells has been identified as a reason for inefficient rAAV-2...

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Detalles Bibliográficos
Autores principales: Boyle, Michael P, Enke, Raymond A, Reynolds, Jeffrey B, Mogayzel, Peter J, Guggino, William B, Zeitlin, Pamela L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459113/
https://www.ncbi.nlm.nih.gov/pubmed/16630361
http://dx.doi.org/10.1186/1743-422X-3-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459113/
https://www.ncbi.nlm.nih.gov/pubmed/16630361
http://dx.doi.org/10.1186/1743-422X-3-29

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