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Fast rate of evolution in alternatively spliced coding regions of mammalian genes

BACKGROUND: At least half of mammalian genes are alternatively spliced. Alternative isoforms are often genome-specific and it has been suggested that alternative splicing is one of the major mechanisms for generating protein diversity in the course of evolution. Another way of looking at alternative...

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Detalles Bibliográficos
Autores principales: Ermakova, Ekaterina O, Nurtdinov, Ramil N, Gelfand, Mikhail S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459143/
https://www.ncbi.nlm.nih.gov/pubmed/16620375
http://dx.doi.org/10.1186/1471-2164-7-84