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3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases

BACKGROUND: Metastasis is a major cause of morbidity and mortality in breast cancer with tumor cell invasion playing a crucial role in the metastatic process. PDK1 is a key molecule that couples PI3K to cell proliferation and survival signals in response to growth factor receptor activation, and is...

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Detalles Bibliográficos
Autores principales:	Xie, Zhihui, Yuan, Hongyan, Yin, Yuzhi, Zeng, Xiao, Bai, Renkui, Glazer, Robert I
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459872/ https://www.ncbi.nlm.nih.gov/pubmed/16551362 http://dx.doi.org/10.1186/1471-2407-6-77

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