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Pulmonary reactions to organic dust exposures: development of an animal model.

Acute inhalation of organic dusts such as cotton, hay, silage, grain, animal confinement, or compost dust can result in illness characterized by fever, pulmonary inflammation, chest tightness, and airway obstruction. These agricultural materials are complex mixtures of plant, bacterial, and fungal p...

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Detalles Bibliográficos
Autores principales: Castranova, V, Robinson, V A, Frazer, D G
Formato: Texto
Lenguaje:English
Publicado: 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469574/
https://www.ncbi.nlm.nih.gov/pubmed/8722109
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author Castranova, V
Robinson, V A
Frazer, D G
author_facet Castranova, V
Robinson, V A
Frazer, D G
author_sort Castranova, V
collection PubMed
description Acute inhalation of organic dusts such as cotton, hay, silage, grain, animal confinement, or compost dust can result in illness characterized by fever, pulmonary inflammation, chest tightness, and airway obstruction. These agricultural materials are complex mixtures of plant, bacterial, and fungal products. Elucidation of the time course of disease onset, the mechanisms of disease progression, and the identity of etiologic agents is essential for effective prevention and treatment. Toward this end, animal models for acute organic dust-induced reactions have been developed and characterized. Information concerning the applicability of various animal models to humans and progress toward elucidation of causative agents and mechanisms of action is presented.
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spelling pubmed-14695742006-06-01 Pulmonary reactions to organic dust exposures: development of an animal model. Castranova, V Robinson, V A Frazer, D G Environ Health Perspect Research Article Acute inhalation of organic dusts such as cotton, hay, silage, grain, animal confinement, or compost dust can result in illness characterized by fever, pulmonary inflammation, chest tightness, and airway obstruction. These agricultural materials are complex mixtures of plant, bacterial, and fungal products. Elucidation of the time course of disease onset, the mechanisms of disease progression, and the identity of etiologic agents is essential for effective prevention and treatment. Toward this end, animal models for acute organic dust-induced reactions have been developed and characterized. Information concerning the applicability of various animal models to humans and progress toward elucidation of causative agents and mechanisms of action is presented. 1996-03 /pmc/articles/PMC1469574/ /pubmed/8722109 Text en
spellingShingle Research Article
Castranova, V
Robinson, V A
Frazer, D G
Pulmonary reactions to organic dust exposures: development of an animal model.
title Pulmonary reactions to organic dust exposures: development of an animal model.
title_full Pulmonary reactions to organic dust exposures: development of an animal model.
title_fullStr Pulmonary reactions to organic dust exposures: development of an animal model.
title_full_unstemmed Pulmonary reactions to organic dust exposures: development of an animal model.
title_short Pulmonary reactions to organic dust exposures: development of an animal model.
title_sort pulmonary reactions to organic dust exposures: development of an animal model.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469574/
https://www.ncbi.nlm.nih.gov/pubmed/8722109
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