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The challenge of mechanism-based modeling in risk assessment for neurobehavioral end points.
The mathematical form for a dose-time-response model is ideally not just a convenience for summarizing or fitting a particular data set--it represents a hypothesis. The more this hypothesis reflects a mechanistically sophisticated view of the likely reality, the more it can lead to potentially infor...
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Formato: | Texto |
Lenguaje: | English |
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1996
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469589/ https://www.ncbi.nlm.nih.gov/pubmed/9182045 |