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Neurobehavioral epidemiology: application in risk assessment.
Neurobehavioral epidemiology may contribute information to risk assessment in relation to a) characterization of neurotoxicity and its time course; b) the dose-effect relationship; c) the dose-response relationship; and d) predisposing factors. The quality of this information relies on the validity...
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469607/ https://www.ncbi.nlm.nih.gov/pubmed/9182047 |
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author | Grandjean, P White, R F Weihe, P |
author_facet | Grandjean, P White, R F Weihe, P |
author_sort | Grandjean, P |
collection | PubMed |
description | Neurobehavioral epidemiology may contribute information to risk assessment in relation to a) characterization of neurotoxicity and its time course; b) the dose-effect relationship; c) the dose-response relationship; and d) predisposing factors. The quality of this information relies on the validity of the exposure data, the validity and sensitivity of neurobehavioral function tests, and the degree to which sources of bias are controlled. With epidemiologic studies of methylmercury-associated neurotoxicity as an example, the field of research involves numerous uncertainties that should be taken into account in the risk assessment process. |
format | Text |
id | pubmed-1469607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1996 |
record_format | MEDLINE/PubMed |
spelling | pubmed-14696072006-06-01 Neurobehavioral epidemiology: application in risk assessment. Grandjean, P White, R F Weihe, P Environ Health Perspect Research Article Neurobehavioral epidemiology may contribute information to risk assessment in relation to a) characterization of neurotoxicity and its time course; b) the dose-effect relationship; c) the dose-response relationship; and d) predisposing factors. The quality of this information relies on the validity of the exposure data, the validity and sensitivity of neurobehavioral function tests, and the degree to which sources of bias are controlled. With epidemiologic studies of methylmercury-associated neurotoxicity as an example, the field of research involves numerous uncertainties that should be taken into account in the risk assessment process. 1996-04 /pmc/articles/PMC1469607/ /pubmed/9182047 Text en |
spellingShingle | Research Article Grandjean, P White, R F Weihe, P Neurobehavioral epidemiology: application in risk assessment. |
title | Neurobehavioral epidemiology: application in risk assessment. |
title_full | Neurobehavioral epidemiology: application in risk assessment. |
title_fullStr | Neurobehavioral epidemiology: application in risk assessment. |
title_full_unstemmed | Neurobehavioral epidemiology: application in risk assessment. |
title_short | Neurobehavioral epidemiology: application in risk assessment. |
title_sort | neurobehavioral epidemiology: application in risk assessment. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469607/ https://www.ncbi.nlm.nih.gov/pubmed/9182047 |
work_keys_str_mv | AT grandjeanp neurobehavioralepidemiologyapplicationinriskassessment AT whiterf neurobehavioralepidemiologyapplicationinriskassessment AT weihep neurobehavioralepidemiologyapplicationinriskassessment |