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Oxidative damage to DNA: do we have a reliable biomarker?

Oxidized bases in DNA can be measured directly by high-performance liquid chromatography (HPLC). 7,8-Dihydro-8-oxo-guanine (8-OHgua), as the most abundant oxidation product, is often regarded as an indicator of oxidative stress. Estimates of endogenous 8-OHgua levels in human lymphocyte DNA are betw...

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Detalles Bibliográficos
Autores principales: Collins, A R, Dusinská, M, Gedik, C M, Stĕtina, R
Formato: Texto
Lenguaje:English
Publicado: 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469644/
https://www.ncbi.nlm.nih.gov/pubmed/8781365