Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.

The Syrian hamster embryo (SHE) cell transformation assay was used to predict the carcinogenicity of 26 chemicals currently being tested in the rodent bioassay by the National Toxicology Program as part of its program titled "Strategies for Predicting Chemical Carcinogenesis in Rodents." O...

Descripción completa

Detalles Bibliográficos
Autores principales: Kerckaert, G A, Brauninger, R, LeBoeuf, R A, Isfort, R J
Formato: Texto
Lenguaje:English
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469685/
https://www.ncbi.nlm.nih.gov/pubmed/8933057
_version_ 1782127663404548096
author Kerckaert, G A
Brauninger, R
LeBoeuf, R A
Isfort, R J
author_facet Kerckaert, G A
Brauninger, R
LeBoeuf, R A
Isfort, R J
author_sort Kerckaert, G A
collection PubMed
description The Syrian hamster embryo (SHE) cell transformation assay was used to predict the carcinogenicity of 26 chemicals currently being tested in the rodent bioassay by the National Toxicology Program as part of its program titled "Strategies for Predicting Chemical Carcinogenesis in Rodents." Of these 26 chemicals, 17 were found to be positive in the SHE cell transformation assay while 9 were negative. Carcinogenicity predictions were made for these chemicals, based upon the SHE cell transformation assay results. Our predictions will be compared with the rodent bioassay results as they become available.
format Text
id pubmed-1469685
institution National Center for Biotechnology Information
language English
publishDate 1996
record_format MEDLINE/PubMed
spelling pubmed-14696852006-06-01 Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays. Kerckaert, G A Brauninger, R LeBoeuf, R A Isfort, R J Environ Health Perspect Research Article The Syrian hamster embryo (SHE) cell transformation assay was used to predict the carcinogenicity of 26 chemicals currently being tested in the rodent bioassay by the National Toxicology Program as part of its program titled "Strategies for Predicting Chemical Carcinogenesis in Rodents." Of these 26 chemicals, 17 were found to be positive in the SHE cell transformation assay while 9 were negative. Carcinogenicity predictions were made for these chemicals, based upon the SHE cell transformation assay results. Our predictions will be compared with the rodent bioassay results as they become available. 1996-10 /pmc/articles/PMC1469685/ /pubmed/8933057 Text en
spellingShingle Research Article
Kerckaert, G A
Brauninger, R
LeBoeuf, R A
Isfort, R J
Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.
title Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.
title_full Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.
title_fullStr Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.
title_full_unstemmed Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.
title_short Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays.
title_sort use of the syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the national toxicology program in rodent bioassays.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469685/
https://www.ncbi.nlm.nih.gov/pubmed/8933057
work_keys_str_mv AT kerckaertga useofthesyrianhamsterembryocelltransformationassayforcarcinogenicitypredictionofchemicalscurrentlybeingtestedbythenationaltoxicologyprograminrodentbioassays
AT brauningerr useofthesyrianhamsterembryocelltransformationassayforcarcinogenicitypredictionofchemicalscurrentlybeingtestedbythenationaltoxicologyprograminrodentbioassays
AT leboeufra useofthesyrianhamsterembryocelltransformationassayforcarcinogenicitypredictionofchemicalscurrentlybeingtestedbythenationaltoxicologyprograminrodentbioassays
AT isfortrj useofthesyrianhamsterembryocelltransformationassayforcarcinogenicitypredictionofchemicalscurrentlybeingtestedbythenationaltoxicologyprograminrodentbioassays

Ejemplares similares