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A mechanism-mediated model for carcinogenicity: model content and prediction of the outcome of rodent carcinogenicity bioassays currently being conducted on 25 organic chemicals.
A hierarchical model consisting of quantitative structure-activity relationships based mainly on chemical reactivity was developed to predict the carcinogenicity of organic chemicals to rodents. The model is comprised of quantitative structure-activity relationships, QSARs based on hypothesized mech...
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| Formato: | Texto |
| Lenguaje: | English |
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1996
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469711/ https://www.ncbi.nlm.nih.gov/pubmed/8933058 |