Cargando…
The use of protein adducts to investigate the disposition of reactive metabolites of benzene.
Benzene is metabolized to a number of electrophilic species that are capable of binding to both DNA and proteins. We used adducts of hemoglobin (Hb) and bone marrow proteins to study the disposition of three benzene and metabolites (benzene oxide [BO], 1,2-benzoquinone [1,2-BQ], and 1,4-benzoquinone...
Autores principales: | Rappaport, S M, McDonald, T A, Yeowell-O'Connell, K |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
1996
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469719/ https://www.ncbi.nlm.nih.gov/pubmed/9118898 |
Ejemplares similares
-
Albumin Adducts of Electrophilic Benzene Metabolites in Benzene-Exposed and Control Workers
por: Lin, Yu-Sheng, et al.
Publicado: (2007) -
Investigation of benzene-DNA adducts and their detection in human bone marrow.
por: Bodell, W J, et al.
Publicado: (1993) -
Characterization of Model Peptide Adducts with Reactive Metabolites of Naphthalene by Mass Spectrometry
por: Pham, Nathalie T., et al.
Publicado: (2012) -
Reactive ring-opened aldehyde metabolites in benzene hematotoxicity.
por: Witz, G, et al.
Publicado: (1996) -
Pyrrolizidine Alkaloid-Induced Hepatotoxicity Associated with the Formation of Reactive Metabolite-Derived Pyrrole–Protein Adducts
por: Ma, Jiang, et al.
Publicado: (2021)