Carcinogenic potential of benzene and toluene when evaluated using cyclin-dependent kinase activation and p53-DNA binding.

Benzene is carcinogenic, whereas toluene is thought to have little carcinogenic potential. Benzene and toluene were found to activate cyclin-dependent kinase 2 in rat liver epithelial (RLE) and HL60 cells. pRb105 was hyperphosphorylated in RLE cells treated with either solvent. Kinase activation and...

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Detalles Bibliográficos
Autores principales: Dees, C, Askari, M, Henley, D
Formato: Texto
Lenguaje:English
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469723/
https://www.ncbi.nlm.nih.gov/pubmed/9118908

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