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Tissue distribution of DNA adducts and their persistence in blood of mice exposed to benzene.
Chemicals combine with DNA, resulting in DNA damage, which could initiate carcinogenesis. To study whether benzene or benzene metabolites bind to DNA, DNA adducts in various tissues and their persistence in leukocytes were examined using the 32P-postlabeling assay. LACA mice were dosed ip with benze...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1469730/ https://www.ncbi.nlm.nih.gov/pubmed/9118916 |