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Alterations in the K-ras and p53 genes in rat lung tumors.
Activation of the K-ras protooncogene and inactivation of the p53 tumor suppressor gene are events common to many types of human cancers. Molecular epidemiology studies have associated mutational profiles in these genes with specific exposures. The purpose of this paper is to review investigations t...
Autores principales: | Belinsky, S A, Swafford, D S, Finch, G L, Mitchell, C E, Kelly, G, Hahn, F F, Anderson, M W, Nikula, K J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470039/ https://www.ncbi.nlm.nih.gov/pubmed/9255578 |
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