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Short-term inhalation and in vitro tests as predictors of fiber pathogenicity.
A wide range of fiber types was tested in two in vitro assays: toxicity to A549 epithelial cells, as detachment from substrate, and the production of the proinflammatory cytokine tumor necrosis factor (TNF) by rat alveolar macrophages. Three of the fibers were also studied in vivo, using short-term...
Autores principales: | Cullen, R T, Miller, B G, Davis, J M, Brown, D M, Donaldson, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470121/ https://www.ncbi.nlm.nih.gov/pubmed/9400730 |
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