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Regulation of progesterone receptor signaling by BRCA1 in mammary cancer
Inherited mutations of the BRCA1 gene (chromosome 17q21), a tumor suppressor, lead to an increased risk of breast cancer, ovarian cancer, and several other hormone-responsive tumor types. Over the last ten years, BRCA1 has been found to play major roles in DNA damage signaling, repair, and cell cycl...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Nuclear Receptor Signaling Atlas
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472667/ https://www.ncbi.nlm.nih.gov/pubmed/16741564 http://dx.doi.org/10.1621/nrs.04006 |