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Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity

BACKGROUND: The pim family genes encode oncogenic serine/threonine kinases which in hematopoietic cells have been implicated in cytokine-dependent signaling as well as in lymphomagenesis, especially in cooperation with other oncogenes such as myc, bcl-2 or Runx family genes. The Runx genes encode α-...

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Detalles Bibliográficos
Autores principales:	Aho, Teija LT, Sandholm, Jouko, Peltola, Katriina J, Ito, Yoshiaki, Koskinen, Päivi J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1473194/ https://www.ncbi.nlm.nih.gov/pubmed/16684349 http://dx.doi.org/10.1186/1471-2121-7-21

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