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Substitutions of Thr30 provide mechanistic insight into tryptophan-mediated activation of TRAP binding to RNA
TRAP is an 11 subunit RNA binding protein that regulates expression of genes involved in tryptophan biosynthesis and transport in Bacillus subtilis. TRAP is activated to bind RNA by binding up to 11 molecules of l-tryptophan in pockets formed by adjacent subunits. The precise mechanism by which tryp...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474065/ https://www.ncbi.nlm.nih.gov/pubmed/16738132 http://dx.doi.org/10.1093/nar/gkl383 |