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Binding and distribution studies in the SENCAR mouse of compounds demonstrating a route-dependent tumorigenic effect.

Previous investigators have determined that benzo(a)pyrene [B(a)P] was much more effective in causing skin papillomas if applied topically than when administered orally in the initiation-promotion assay in SENCAR mouse. Conversely, urethane and acrylamide caused a higher percentage of mice to develo...

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Detalles Bibliográficos
Autores principales: Carlson, G P, Fossa, A A, Morse, M A, Weaver, P M
Formato: Texto
Lenguaje:English
Publicado: 1986
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474256/
https://www.ncbi.nlm.nih.gov/pubmed/3780633