Results of in vivo and in vitro studies for assessing prenatal toxicity

Examples of a combined approach using in vivo as well as in vitro methods for the assessment of prenatal toxicity are presented. The topics discussed include the analysis of the possible embryotoxic potential of valproic acid (VPA), female sex hormones, bis(tri-n-butyltin) oxide (TBTO), and acyclovi...

Descripción completa

Detalles Bibliográficos
Autores principales: Neubert, Diether, Blankenburg, Gudrun, Chahoud, Ibrahim, Franz, Gabriele, Herken, Rainer, Kastner, Michael, Klug, Stephan, Kröger, Joachim, Krowke, Ralf, Lewandowski, Constanze, Merker, Hans-Joachim, Schulz, Thomas, Stahlmann, Ralf
Formato: Texto
Lenguaje:English
Publicado: 1986
Materias:
Mechanisms of Teratogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474293/
https://www.ncbi.nlm.nih.gov/pubmed/3104025
_version_ 1782127877467144192
author Neubert, Diether
Blankenburg, Gudrun
Chahoud, Ibrahim
Franz, Gabriele
Herken, Rainer
Kastner, Michael
Klug, Stephan
Kröger, Joachim
Krowke, Ralf
Lewandowski, Constanze
Merker, Hans-Joachim
Schulz, Thomas
Stahlmann, Ralf
author_facet Neubert, Diether
Blankenburg, Gudrun
Chahoud, Ibrahim
Franz, Gabriele
Herken, Rainer
Kastner, Michael
Klug, Stephan
Kröger, Joachim
Krowke, Ralf
Lewandowski, Constanze
Merker, Hans-Joachim
Schulz, Thomas
Stahlmann, Ralf
author_sort Neubert, Diether
collection PubMed
description Examples of a combined approach using in vivo as well as in vitro methods for the assessment of prenatal toxicity are presented. The topics discussed include the analysis of the possible embryotoxic potential of valproic acid (VPA), female sex hormones, bis(tri-n-butyltin) oxide (TBTO), and acyclovir and the problem of supplementing in vitro systems with drug-metabolizing activity.
format Text
id pubmed-1474293
institution National Center for Biotechnology Information
language English
publishDate 1986
record_format MEDLINE/PubMed
spelling pubmed-14742932006-06-09 Results of in vivo and in vitro studies for assessing prenatal toxicity Neubert, Diether Blankenburg, Gudrun Chahoud, Ibrahim Franz, Gabriele Herken, Rainer Kastner, Michael Klug, Stephan Kröger, Joachim Krowke, Ralf Lewandowski, Constanze Merker, Hans-Joachim Schulz, Thomas Stahlmann, Ralf Environ Health Perspect Mechanisms of Teratogenesis Examples of a combined approach using in vivo as well as in vitro methods for the assessment of prenatal toxicity are presented. The topics discussed include the analysis of the possible embryotoxic potential of valproic acid (VPA), female sex hormones, bis(tri-n-butyltin) oxide (TBTO), and acyclovir and the problem of supplementing in vitro systems with drug-metabolizing activity. 1986-12 /pmc/articles/PMC1474293/ /pubmed/3104025 Text en
spellingShingle Mechanisms of Teratogenesis
Neubert, Diether
Blankenburg, Gudrun
Chahoud, Ibrahim
Franz, Gabriele
Herken, Rainer
Kastner, Michael
Klug, Stephan
Kröger, Joachim
Krowke, Ralf
Lewandowski, Constanze
Merker, Hans-Joachim
Schulz, Thomas
Stahlmann, Ralf
Results of in vivo and in vitro studies for assessing prenatal toxicity
title Results of in vivo and in vitro studies for assessing prenatal toxicity
title_full Results of in vivo and in vitro studies for assessing prenatal toxicity
title_fullStr Results of in vivo and in vitro studies for assessing prenatal toxicity
title_full_unstemmed Results of in vivo and in vitro studies for assessing prenatal toxicity
title_short Results of in vivo and in vitro studies for assessing prenatal toxicity
title_sort results of in vivo and in vitro studies for assessing prenatal toxicity
topic Mechanisms of Teratogenesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474293/
https://www.ncbi.nlm.nih.gov/pubmed/3104025
work_keys_str_mv AT neubertdiether resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT blankenburggudrun resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT chahoudibrahim resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT franzgabriele resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT herkenrainer resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT kastnermichael resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT klugstephan resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT krogerjoachim resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT krowkeralf resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT lewandowskiconstanze resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT merkerhansjoachim resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT schulzthomas resultsofinvivoandinvitrostudiesforassessingprenataltoxicity
AT stahlmannralf resultsofinvivoandinvitrostudiesforassessingprenataltoxicity

Ejemplares similares