Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.

We have found several similarities between tannic acid and grain dust extract prepared with methanol. Both formed a precipitate with IgG, and these interactions were inhibited by albumin. In addition, both preparations fixed complement; this activity was heat stable and was removed by prior adsorpti...

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Detalles Bibliográficos
Autores principales: Skea, D, Broder, I
Formato: Texto
Lenguaje:English
Publicado: 1986
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474384/
https://www.ncbi.nlm.nih.gov/pubmed/3709479
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author Skea, D
Broder, I
author_facet Skea, D
Broder, I
author_sort Skea, D
collection PubMed
description We have found several similarities between tannic acid and grain dust extract prepared with methanol. Both formed a precipitate with IgG, and these interactions were inhibited by albumin. In addition, both preparations fixed complement; this activity was heat stable and was removed by prior adsorption of the preparations with hide powder. Adsorption with polyvinyl polypyrrolidone reduced the complement-fixing activity of tannic acid but not that of the methanol grain dust extract. The similarities between tannic acid and the methanol grain dust extract are consistent with the presence of a tannin or tanninlike material in grain dust.
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spelling pubmed-14743842006-06-09 Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid. Skea, D Broder, I Environ Health Perspect Research Article We have found several similarities between tannic acid and grain dust extract prepared with methanol. Both formed a precipitate with IgG, and these interactions were inhibited by albumin. In addition, both preparations fixed complement; this activity was heat stable and was removed by prior adsorption of the preparations with hide powder. Adsorption with polyvinyl polypyrrolidone reduced the complement-fixing activity of tannic acid but not that of the methanol grain dust extract. The similarities between tannic acid and the methanol grain dust extract are consistent with the presence of a tannin or tanninlike material in grain dust. 1986-04 /pmc/articles/PMC1474384/ /pubmed/3709479 Text en
spellingShingle Research Article
Skea, D
Broder, I
Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
title Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
title_full Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
title_fullStr Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
title_full_unstemmed Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
title_short Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
title_sort methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474384/
https://www.ncbi.nlm.nih.gov/pubmed/3709479
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AT broderi methanolextractofgraindustshowscomplementfixingactivityandothercharacteristicssimilartotannicacid

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