Synthesis and radiolabeling of heterocyclic food mutagens.

The imidazoquinoline and imidazoquinoxaline food mutagens found in cooked meat are being synthesized by unambiguous methods that allow for the preparation of sufficient quantities of material for biological studies. These methods avoid difficult separations of regioisomeric mixtures of products and...

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Detalles Bibliográficos
Autores principales: Rapoport, H, Waterhouse, A L, Thompson, C M, O'Connell, J F
Formato: Texto
Lenguaje:English
Publicado: 1986
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474401/
https://www.ncbi.nlm.nih.gov/pubmed/3757958
Descripción
Sumario:The imidazoquinoline and imidazoquinoxaline food mutagens found in cooked meat are being synthesized by unambiguous methods that allow for the preparation of sufficient quantities of material for biological studies. These methods avoid difficult separations of regioisomeric mixtures of products and are designed to allow incorporation of specific high level tritium labeling.

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