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Role of protein kinase C in regulation of gene expression and relevance to tumor promotion.
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) has highly pleiotropic effects on cells in culture and on tissues in vivo, including effects on protein kinase C (PKC) activation and gene expression. In order to determine the mechanism of activation of gene transcription by TPA, DNA seq...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1987
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474480/ https://www.ncbi.nlm.nih.gov/pubmed/2452080 |