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Role of protein kinase C in regulation of gene expression and relevance to tumor promotion.

The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) has highly pleiotropic effects on cells in culture and on tissues in vivo, including effects on protein kinase C (PKC) activation and gene expression. In order to determine the mechanism of activation of gene transcription by TPA, DNA seq...

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Detalles Bibliográficos
Autores principales: Johnson, M D, Housey, G M, O'Brian, C A, Kirschmeier, P T, Weinstein, I B
Formato: Texto
Lenguaje:English
Publicado: 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474480/
https://www.ncbi.nlm.nih.gov/pubmed/2452080