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Comparative results of 327 chemical carcinogenicity studies.
The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried ou...
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Formato: | Texto |
Lenguaje: | English |
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1987
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474512/ https://www.ncbi.nlm.nih.gov/pubmed/3691430 |
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author | Haseman, J K Huff, J E Zeiger, E McConnell, E E |
author_facet | Haseman, J K Huff, J E Zeiger, E McConnell, E E |
author_sort | Haseman, J K |
collection | PubMed |
description | The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried out to date on 308 distinct chemicals, and discusses certain issues relevant to the evaluation of carcinogenicity in these experiments. This compilation of results from NCI/NTP carcinogenicity experiments provides a large database that can be used to study structure-activity correlations, interspecies concordance, and associations between laboratory animal carcinogenicity and other toxicological effects. |
format | Text |
id | pubmed-1474512 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1987 |
record_format | MEDLINE/PubMed |
spelling | pubmed-14745122006-06-09 Comparative results of 327 chemical carcinogenicity studies. Haseman, J K Huff, J E Zeiger, E McConnell, E E Environ Health Perspect Research Article The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried out to date on 308 distinct chemicals, and discusses certain issues relevant to the evaluation of carcinogenicity in these experiments. This compilation of results from NCI/NTP carcinogenicity experiments provides a large database that can be used to study structure-activity correlations, interspecies concordance, and associations between laboratory animal carcinogenicity and other toxicological effects. 1987-10 /pmc/articles/PMC1474512/ /pubmed/3691430 Text en |
spellingShingle | Research Article Haseman, J K Huff, J E Zeiger, E McConnell, E E Comparative results of 327 chemical carcinogenicity studies. |
title | Comparative results of 327 chemical carcinogenicity studies. |
title_full | Comparative results of 327 chemical carcinogenicity studies. |
title_fullStr | Comparative results of 327 chemical carcinogenicity studies. |
title_full_unstemmed | Comparative results of 327 chemical carcinogenicity studies. |
title_short | Comparative results of 327 chemical carcinogenicity studies. |
title_sort | comparative results of 327 chemical carcinogenicity studies. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474512/ https://www.ncbi.nlm.nih.gov/pubmed/3691430 |
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