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Comparative results of 327 chemical carcinogenicity studies.

The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried ou...

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Detalles Bibliográficos
Autores principales: Haseman, J K, Huff, J E, Zeiger, E, McConnell, E E
Formato: Texto
Lenguaje:English
Publicado: 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474512/
https://www.ncbi.nlm.nih.gov/pubmed/3691430
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author Haseman, J K
Huff, J E
Zeiger, E
McConnell, E E
author_facet Haseman, J K
Huff, J E
Zeiger, E
McConnell, E E
author_sort Haseman, J K
collection PubMed
description The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried out to date on 308 distinct chemicals, and discusses certain issues relevant to the evaluation of carcinogenicity in these experiments. This compilation of results from NCI/NTP carcinogenicity experiments provides a large database that can be used to study structure-activity correlations, interspecies concordance, and associations between laboratory animal carcinogenicity and other toxicological effects.
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spelling pubmed-14745122006-06-09 Comparative results of 327 chemical carcinogenicity studies. Haseman, J K Huff, J E Zeiger, E McConnell, E E Environ Health Perspect Research Article The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried out to date on 308 distinct chemicals, and discusses certain issues relevant to the evaluation of carcinogenicity in these experiments. This compilation of results from NCI/NTP carcinogenicity experiments provides a large database that can be used to study structure-activity correlations, interspecies concordance, and associations between laboratory animal carcinogenicity and other toxicological effects. 1987-10 /pmc/articles/PMC1474512/ /pubmed/3691430 Text en
spellingShingle Research Article
Haseman, J K
Huff, J E
Zeiger, E
McConnell, E E
Comparative results of 327 chemical carcinogenicity studies.
title Comparative results of 327 chemical carcinogenicity studies.
title_full Comparative results of 327 chemical carcinogenicity studies.
title_fullStr Comparative results of 327 chemical carcinogenicity studies.
title_full_unstemmed Comparative results of 327 chemical carcinogenicity studies.
title_short Comparative results of 327 chemical carcinogenicity studies.
title_sort comparative results of 327 chemical carcinogenicity studies.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474512/
https://www.ncbi.nlm.nih.gov/pubmed/3691430
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