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Functional evidence of persistent airway obstruction in rats following a two-hour inhalation exposure to methyl isocyanate.
Pulmonary function was assessed in male, F344 rats 1,2,4,7, and 13 weeks after a single 2-hr exposure to 0, 3, 10, or 30 ppm methyl isocyanate. No significant changes were observed in the rats exposed to 3 ppm through 13 weeks. Diffusing capacity (DLco), quasistatic lung compliance, and homogeneity...
Autores principales: | Stevens, M A, Fitzgerald, S, Ménache, M G, Costa, D L, Bucher, J R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1987
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474629/ https://www.ncbi.nlm.nih.gov/pubmed/3622448 |
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