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Teratological research using in vitro systems. V. Nonmammalian model systems.
In this review of alternative tests to whole-animal rodent studies, the use of sub-mammalian and sub-vertebrate systems is investigated. The history, methodology, known limitations, end points, dose response, and requirements of virus, hydra, planarian, cricket, fish, amphibia, Drosophila, and chick...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1987
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474641/ https://www.ncbi.nlm.nih.gov/pubmed/3113934 |
| Sumario: | In this review of alternative tests to whole-animal rodent studies, the use of sub-mammalian and sub-vertebrate systems is investigated. The history, methodology, known limitations, end points, dose response, and requirements of virus, hydra, planarian, cricket, fish, amphibia, Drosophila, and chicken embryo systems are discussed. |
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