Whole body retention in rats of different 191Pt compounds following inhalation exposure.

The whole body retention, excretion, lung clearance, distribution, and concentration of 191Pt in other tissues was determined in rats following a single inhalation exposure to different chemical forms of 191Pt. The chemical forms of 191Pt used in study were 191PtCl4, 191Pt(SO4)2, 191PtO, and 191Pt m...

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Detalles Bibliográficos
Autores principales: Moore, W, Malanchuk, M, Crocker, W, Hysell, D, Cohen, A, Stara, J F
Formato: Texto
Lenguaje:English
Publicado: 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475035/
https://www.ncbi.nlm.nih.gov/pubmed/1227859
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author Moore, W
Malanchuk, M
Crocker, W
Hysell, D
Cohen, A
Stara, J F
author_facet Moore, W
Malanchuk, M
Crocker, W
Hysell, D
Cohen, A
Stara, J F
author_sort Moore, W
collection PubMed
description The whole body retention, excretion, lung clearance, distribution, and concentration of 191Pt in other tissues was determined in rats following a single inhalation exposure to different chemical forms of 191Pt. The chemical forms of 191Pt used in study were 191PtCl4, 191Pt(SO4)2, 191PtO, and 191Pt metal. Immediately after exposure most of the 191Pt was found in the gastrointestinal and respiratory tract. Movement of the 191Pt through the gastrointestinal tract was rapid, most of the 191Pt being eliminated within 24 hr after exposure. Lung clearance was much slower, with a clearance half-time of about 8 days. In addition to the lungs, kidney and bone contained the highest concentrations of 191Pt.
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spelling pubmed-14750352006-06-09 Whole body retention in rats of different 191Pt compounds following inhalation exposure. Moore, W Malanchuk, M Crocker, W Hysell, D Cohen, A Stara, J F Environ Health Perspect Research Article The whole body retention, excretion, lung clearance, distribution, and concentration of 191Pt in other tissues was determined in rats following a single inhalation exposure to different chemical forms of 191Pt. The chemical forms of 191Pt used in study were 191PtCl4, 191Pt(SO4)2, 191PtO, and 191Pt metal. Immediately after exposure most of the 191Pt was found in the gastrointestinal and respiratory tract. Movement of the 191Pt through the gastrointestinal tract was rapid, most of the 191Pt being eliminated within 24 hr after exposure. Lung clearance was much slower, with a clearance half-time of about 8 days. In addition to the lungs, kidney and bone contained the highest concentrations of 191Pt. 1975-12 /pmc/articles/PMC1475035/ /pubmed/1227859 Text en
spellingShingle Research Article
Moore, W
Malanchuk, M
Crocker, W
Hysell, D
Cohen, A
Stara, J F
Whole body retention in rats of different 191Pt compounds following inhalation exposure.
title Whole body retention in rats of different 191Pt compounds following inhalation exposure.
title_full Whole body retention in rats of different 191Pt compounds following inhalation exposure.
title_fullStr Whole body retention in rats of different 191Pt compounds following inhalation exposure.
title_full_unstemmed Whole body retention in rats of different 191Pt compounds following inhalation exposure.
title_short Whole body retention in rats of different 191Pt compounds following inhalation exposure.
title_sort whole body retention in rats of different 191pt compounds following inhalation exposure.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475035/
https://www.ncbi.nlm.nih.gov/pubmed/1227859
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AT crockerw wholebodyretentioninratsofdifferent191ptcompoundsfollowinginhalationexposure
AT hyselld wholebodyretentioninratsofdifferent191ptcompoundsfollowinginhalationexposure
AT cohena wholebodyretentioninratsofdifferent191ptcompoundsfollowinginhalationexposure
AT starajf wholebodyretentioninratsofdifferent191ptcompoundsfollowinginhalationexposure

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