Metabolism and toxicity of styrene.

The absorption, blood levels, distribution, excretion, and biotransformation of styrene in man and experimental animals are briefly reviewed. The acute toxicity of styrene appears to be unrelated to its biotransformation. Reports of organ toxicity upon chronic exposure to styrene are rare; however,...

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Detalles Bibliográficos
Autor principal: Leibman, K C
Formato: Texto
Lenguaje:English
Publicado: 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475194/
https://www.ncbi.nlm.nih.gov/pubmed/809262
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author Leibman, K C
author_facet Leibman, K C
author_sort Leibman, K C
collection PubMed
description The absorption, blood levels, distribution, excretion, and biotransformation of styrene in man and experimental animals are briefly reviewed. The acute toxicity of styrene appears to be unrelated to its biotransformation. Reports of organ toxicity upon chronic exposure to styrene are rare; however, since the chief intermediate in styrene metabolism is an epoxide, hepatotoxicity due to covalent binding at the site of formation appears to be a possibility.
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spelling pubmed-14751942006-06-09 Metabolism and toxicity of styrene. Leibman, K C Environ Health Perspect Research Article The absorption, blood levels, distribution, excretion, and biotransformation of styrene in man and experimental animals are briefly reviewed. The acute toxicity of styrene appears to be unrelated to its biotransformation. Reports of organ toxicity upon chronic exposure to styrene are rare; however, since the chief intermediate in styrene metabolism is an epoxide, hepatotoxicity due to covalent binding at the site of formation appears to be a possibility. 1975-06 /pmc/articles/PMC1475194/ /pubmed/809262 Text en
spellingShingle Research Article
Leibman, K C
Metabolism and toxicity of styrene.
title Metabolism and toxicity of styrene.
title_full Metabolism and toxicity of styrene.
title_fullStr Metabolism and toxicity of styrene.
title_full_unstemmed Metabolism and toxicity of styrene.
title_short Metabolism and toxicity of styrene.
title_sort metabolism and toxicity of styrene.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475194/
https://www.ncbi.nlm.nih.gov/pubmed/809262
work_keys_str_mv AT leibmankc metabolismandtoxicityofstyrene

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