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Behavioral testing as a method for assessing risk.

Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant techn...

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Detalles Bibliográficos
Autor principal: Butcher, R E
Formato: Texto
Lenguaje:English
Publicado: 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475305/
https://www.ncbi.nlm.nih.gov/pubmed/1030402
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author Butcher, R E
author_facet Butcher, R E
author_sort Butcher, R E
collection PubMed
description Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant technique for detecting adverse consequences of prenatal exposure to drugs and chemicals. Behavioral testing, however, also appears to have attributes that dictate a thoughtful approach to its role as a method for assessing risk, and additional research is needed to obtain usable techniques. The need for such research is intensified by the present inability to identify potential behavioral teratogens by means other than laboratory investigation.
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spelling pubmed-14753052006-06-09 Behavioral testing as a method for assessing risk. Butcher, R E Environ Health Perspect Research Article Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant technique for detecting adverse consequences of prenatal exposure to drugs and chemicals. Behavioral testing, however, also appears to have attributes that dictate a thoughtful approach to its role as a method for assessing risk, and additional research is needed to obtain usable techniques. The need for such research is intensified by the present inability to identify potential behavioral teratogens by means other than laboratory investigation. 1976-12 /pmc/articles/PMC1475305/ /pubmed/1030402 Text en
spellingShingle Research Article
Butcher, R E
Behavioral testing as a method for assessing risk.
title Behavioral testing as a method for assessing risk.
title_full Behavioral testing as a method for assessing risk.
title_fullStr Behavioral testing as a method for assessing risk.
title_full_unstemmed Behavioral testing as a method for assessing risk.
title_short Behavioral testing as a method for assessing risk.
title_sort behavioral testing as a method for assessing risk.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475305/
https://www.ncbi.nlm.nih.gov/pubmed/1030402
work_keys_str_mv AT butcherre behavioraltestingasamethodforassessingrisk