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Behavioral testing as a method for assessing risk.
Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant techn...
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Formato: | Texto |
Lenguaje: | English |
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1976
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475305/ https://www.ncbi.nlm.nih.gov/pubmed/1030402 |
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author | Butcher, R E |
author_facet | Butcher, R E |
author_sort | Butcher, R E |
collection | PubMed |
description | Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant technique for detecting adverse consequences of prenatal exposure to drugs and chemicals. Behavioral testing, however, also appears to have attributes that dictate a thoughtful approach to its role as a method for assessing risk, and additional research is needed to obtain usable techniques. The need for such research is intensified by the present inability to identify potential behavioral teratogens by means other than laboratory investigation. |
format | Text |
id | pubmed-1475305 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1976 |
record_format | MEDLINE/PubMed |
spelling | pubmed-14753052006-06-09 Behavioral testing as a method for assessing risk. Butcher, R E Environ Health Perspect Research Article Behavioral effects have been found to result from the prenatal administration of substances known to be teratogenic to the CNS. These effects occur at dose levels lower than those producing gross malformations and when the agent is administered at times other than that optimal for CNS relevant technique for detecting adverse consequences of prenatal exposure to drugs and chemicals. Behavioral testing, however, also appears to have attributes that dictate a thoughtful approach to its role as a method for assessing risk, and additional research is needed to obtain usable techniques. The need for such research is intensified by the present inability to identify potential behavioral teratogens by means other than laboratory investigation. 1976-12 /pmc/articles/PMC1475305/ /pubmed/1030402 Text en |
spellingShingle | Research Article Butcher, R E Behavioral testing as a method for assessing risk. |
title | Behavioral testing as a method for assessing risk. |
title_full | Behavioral testing as a method for assessing risk. |
title_fullStr | Behavioral testing as a method for assessing risk. |
title_full_unstemmed | Behavioral testing as a method for assessing risk. |
title_short | Behavioral testing as a method for assessing risk. |
title_sort | behavioral testing as a method for assessing risk. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475305/ https://www.ncbi.nlm.nih.gov/pubmed/1030402 |
work_keys_str_mv | AT butcherre behavioraltestingasamethodforassessingrisk |