Metabolism and toxicology of pyrethroids with dihalovinyl substituents.

Replacement of the photolabile and biodegradable isobutenyl substituent of pyrethroids with a dihalovinyl group often leads to improved insecticidal potency and enhanced photostability. This type of structural modification does not greatly alter the ease of detoxification in mammals since other site...

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Detalles Bibliográficos
Autores principales: Ruzo, L O, Casida, J E
Formato: Texto
Lenguaje:English
Publicado: 1977
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475316/
https://www.ncbi.nlm.nih.gov/pubmed/612453
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author Ruzo, L O
Casida, J E
author_facet Ruzo, L O
Casida, J E
author_sort Ruzo, L O
collection PubMed
description Replacement of the photolabile and biodegradable isobutenyl substituent of pyrethroids with a dihalovinyl group often leads to improved insecticidal potency and enhanced photostability. This type of structural modification does not greatly alter the ease of detoxification in mammals since other sites in the molecule undergo metabolic attack. The available toxicological information on dihalovinyl pyrethroids indicates that they are suitable replacements for other insecticides with less favorable persistence and toxicological characteristics.
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spelling pubmed-14753162006-06-11 Metabolism and toxicology of pyrethroids with dihalovinyl substituents. Ruzo, L O Casida, J E Environ Health Perspect Research Article Replacement of the photolabile and biodegradable isobutenyl substituent of pyrethroids with a dihalovinyl group often leads to improved insecticidal potency and enhanced photostability. This type of structural modification does not greatly alter the ease of detoxification in mammals since other sites in the molecule undergo metabolic attack. The available toxicological information on dihalovinyl pyrethroids indicates that they are suitable replacements for other insecticides with less favorable persistence and toxicological characteristics. 1977-12 /pmc/articles/PMC1475316/ /pubmed/612453 Text en
spellingShingle Research Article
Ruzo, L O
Casida, J E
Metabolism and toxicology of pyrethroids with dihalovinyl substituents.
title Metabolism and toxicology of pyrethroids with dihalovinyl substituents.
title_full Metabolism and toxicology of pyrethroids with dihalovinyl substituents.
title_fullStr Metabolism and toxicology of pyrethroids with dihalovinyl substituents.
title_full_unstemmed Metabolism and toxicology of pyrethroids with dihalovinyl substituents.
title_short Metabolism and toxicology of pyrethroids with dihalovinyl substituents.
title_sort metabolism and toxicology of pyrethroids with dihalovinyl substituents.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475316/
https://www.ncbi.nlm.nih.gov/pubmed/612453
work_keys_str_mv AT ruzolo metabolismandtoxicologyofpyrethroidswithdihalovinylsubstituents
AT casidaje metabolismandtoxicologyofpyrethroidswithdihalovinylsubstituents

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