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1,1-Dichloroethylene hepatotoxicity: Proposed mechanism of action and distribution and binding of (14)C radioactivity following inhalation exposure in rats
1,1-Dichloroethylene is reported to produce renal tumors in male mice. It is an hepatotoxin in fasted rats after inhalation. We found that trichloropropane epoxide, an inhibitor of epoxide hydrase, enhances hepatic injury as measured by serum sorbitol dehydrogenase elevation. A significant elevation...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1977
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475321/ https://www.ncbi.nlm.nih.gov/pubmed/612435 |