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Recent findings on the carcinogenicity of chlorinated olefins.

Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl...

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Detalles Bibliográficos
Autor principal: Maltoni, C
Formato: Texto
Lenguaje:English
Publicado: 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475333/
https://www.ncbi.nlm.nih.gov/pubmed/612433
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author Maltoni, C
author_facet Maltoni, C
author_sort Maltoni, C
collection PubMed
description Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl chloride and vinylidene chloride. Early results, which appear to show that some of these factors (particularly species, strain, and sex) act by affecting the metabolism of the tested compounds, are presented, and the need for metabolic characterization of experimental animals in chemical carcinogenesis is stressed.
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spelling pubmed-14753332006-06-11 Recent findings on the carcinogenicity of chlorinated olefins. Maltoni, C Environ Health Perspect Research Article Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl chloride and vinylidene chloride. Early results, which appear to show that some of these factors (particularly species, strain, and sex) act by affecting the metabolism of the tested compounds, are presented, and the need for metabolic characterization of experimental animals in chemical carcinogenesis is stressed. 1977-12 /pmc/articles/PMC1475333/ /pubmed/612433 Text en
spellingShingle Research Article
Maltoni, C
Recent findings on the carcinogenicity of chlorinated olefins.
title Recent findings on the carcinogenicity of chlorinated olefins.
title_full Recent findings on the carcinogenicity of chlorinated olefins.
title_fullStr Recent findings on the carcinogenicity of chlorinated olefins.
title_full_unstemmed Recent findings on the carcinogenicity of chlorinated olefins.
title_short Recent findings on the carcinogenicity of chlorinated olefins.
title_sort recent findings on the carcinogenicity of chlorinated olefins.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475333/
https://www.ncbi.nlm.nih.gov/pubmed/612433
work_keys_str_mv AT maltonic recentfindingsonthecarcinogenicityofchlorinatedolefins