Cargando…
Recent findings on the carcinogenicity of chlorinated olefins.
Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
1977
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475333/ https://www.ncbi.nlm.nih.gov/pubmed/612433 |
_version_ | 1782128080968482816 |
---|---|
author | Maltoni, C |
author_facet | Maltoni, C |
author_sort | Maltoni, C |
collection | PubMed |
description | Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl chloride and vinylidene chloride. Early results, which appear to show that some of these factors (particularly species, strain, and sex) act by affecting the metabolism of the tested compounds, are presented, and the need for metabolic characterization of experimental animals in chemical carcinogenesis is stressed. |
format | Text |
id | pubmed-1475333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1977 |
record_format | MEDLINE/PubMed |
spelling | pubmed-14753332006-06-11 Recent findings on the carcinogenicity of chlorinated olefins. Maltoni, C Environ Health Perspect Research Article Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl chloride and vinylidene chloride. Early results, which appear to show that some of these factors (particularly species, strain, and sex) act by affecting the metabolism of the tested compounds, are presented, and the need for metabolic characterization of experimental animals in chemical carcinogenesis is stressed. 1977-12 /pmc/articles/PMC1475333/ /pubmed/612433 Text en |
spellingShingle | Research Article Maltoni, C Recent findings on the carcinogenicity of chlorinated olefins. |
title | Recent findings on the carcinogenicity of chlorinated olefins. |
title_full | Recent findings on the carcinogenicity of chlorinated olefins. |
title_fullStr | Recent findings on the carcinogenicity of chlorinated olefins. |
title_full_unstemmed | Recent findings on the carcinogenicity of chlorinated olefins. |
title_short | Recent findings on the carcinogenicity of chlorinated olefins. |
title_sort | recent findings on the carcinogenicity of chlorinated olefins. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475333/ https://www.ncbi.nlm.nih.gov/pubmed/612433 |
work_keys_str_mv | AT maltonic recentfindingsonthecarcinogenicityofchlorinatedolefins |