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Halothane hepatotoxicity and the reduced derivative, 1,1,1-trifluoro-2-chloroethane.
Halothane (1,1,1-trifluoro-2-bromo-2-chloroethane) is a safe, clinically useful inhalation anesthetic. Rare, unpredictable cases of liver necrosis have been reported following its use. Although the mechanism of this reaction in man is unknown the most plausible is biotransformation to reactive inter...
Autores principales: | Brown, B R, Sipes, I G, Baker, R K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1977
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475357/ https://www.ncbi.nlm.nih.gov/pubmed/612444 |
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