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Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products
BACKGROUND: Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role. As recently S100 proteins have been identified as ligands of RAGE, we soug...
Autores principales: | Ehlermann, Philipp, Eggers, Kai, Bierhaus, Angelika, Most, Patrick, Weichenhan, Dieter, Greten, Johannes, Nawroth, Peter P, Katus, Hugo A, Remppis, Andrew |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475836/ https://www.ncbi.nlm.nih.gov/pubmed/16573830 http://dx.doi.org/10.1186/1475-2840-5-6 |
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