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A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

BACKGROUND: Interleukin 4 (IL-4) is a key regulator of the immune system and an important factor in the development of allergic hypersensitivity. Together with interleukin 13 (IL-13), IL-4 plays an important role in exacerbating allergic and asthmatic symptoms. For signal transduction, both cytokine...

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Detalles Bibliográficos
Autores principales:	Kraich, Michael, Klein, Markus, Patiño, Edwin, Harrer, Henning, Nickel, Joachim, Sebald, Walter, Mueller, Thomas D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479839/ https://www.ncbi.nlm.nih.gov/pubmed/16640778 http://dx.doi.org/10.1186/1741-7007-4-13

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