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Tau Phosphorylation, Aggregation, and Cell Toxicity

Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is discussed, focussing on the tau aggregation that takes place in those disorders known as tauopathies.

Detalles Bibliográficos
Autores principales: Avila, J., Santa-María, I., Pérez, M., Hernández, F., Moreno, F.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479889/
https://www.ncbi.nlm.nih.gov/pubmed/17047313
http://dx.doi.org/10.1155/JBB/2006/74539
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author Avila, J.
Santa-María, I.
Pérez, M.
Hernández, F.
Moreno, F.
author_facet Avila, J.
Santa-María, I.
Pérez, M.
Hernández, F.
Moreno, F.
author_sort Avila, J.
collection PubMed
description Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is discussed, focussing on the tau aggregation that takes place in those disorders known as tauopathies.
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spelling pubmed-14798892006-07-18 Tau Phosphorylation, Aggregation, and Cell Toxicity Avila, J. Santa-María, I. Pérez, M. Hernández, F. Moreno, F. J Biomed Biotechnol Review Article Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is discussed, focussing on the tau aggregation that takes place in those disorders known as tauopathies. Hindawi Publishing Corporation 2006 2006 /pmc/articles/PMC1479889/ /pubmed/17047313 http://dx.doi.org/10.1155/JBB/2006/74539 Text en Copyright © 2006 J. Avila et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Avila, J.
Santa-María, I.
Pérez, M.
Hernández, F.
Moreno, F.
Tau Phosphorylation, Aggregation, and Cell Toxicity
title Tau Phosphorylation, Aggregation, and Cell Toxicity
title_full Tau Phosphorylation, Aggregation, and Cell Toxicity
title_fullStr Tau Phosphorylation, Aggregation, and Cell Toxicity
title_full_unstemmed Tau Phosphorylation, Aggregation, and Cell Toxicity
title_short Tau Phosphorylation, Aggregation, and Cell Toxicity
title_sort tau phosphorylation, aggregation, and cell toxicity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479889/
https://www.ncbi.nlm.nih.gov/pubmed/17047313
http://dx.doi.org/10.1155/JBB/2006/74539
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