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Induction of revertant fibres in the mdx mouse using antisense oligonucleotides

BACKGROUND: Duchenne muscular dystrophy is a fatal genetic disorder caused by dystrophin gene mutations that result in premature termination of translation and the absence of functional protein. Despite the primary dystrophin gene lesion, immunostaining studies have shown that at least 50% of DMD pa...

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Detalles Bibliográficos
Autores principales: Fall, Abbie M, Johnsen, Russell, Honeyman, Kaite, Iversen, Pat, Fletcher, Susan, Wilton, Stephen D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481566/
https://www.ncbi.nlm.nih.gov/pubmed/16719929
http://dx.doi.org/10.1186/1479-0556-4-3