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Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report
BACKGROUND: Methylene bis(thiocyanate) (MBT) is a microbiocidal agent mainly used in industrial water cooling systems and paper mills as an inhibitor of algae, fungi, and bacteria. CASE PRESENTATION: We describe the first case of severe intoxication following inhalation of powder in an industrial wo...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481609/ https://www.ncbi.nlm.nih.gov/pubmed/16608508 http://dx.doi.org/10.1186/1471-227X-6-5 |
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author | Braun, Claude Birck, Rainer Singer, Manfred V Schnuelle, Peter van der Woude, Fokko J Löhr, Matthias |
author_facet | Braun, Claude Birck, Rainer Singer, Manfred V Schnuelle, Peter van der Woude, Fokko J Löhr, Matthias |
author_sort | Braun, Claude |
collection | PubMed |
description | BACKGROUND: Methylene bis(thiocyanate) (MBT) is a microbiocidal agent mainly used in industrial water cooling systems and paper mills as an inhibitor of algae, fungi, and bacteria. CASE PRESENTATION: We describe the first case of severe intoxication following inhalation of powder in an industrial worker. Profound cyanosis and respiratory failure caused by severe methemoglobinemia developed within several minutes. Despite immediate admission to the intensive care unit, where mechanical ventilation and hemodialysis for toxin elimination were initiated, multi-organ failure involving liver, kidneys, and lungs developed. While liver failure was leading, the patient was successfully treated with the MARS (molecular adsorbent recirculating system) procedure. CONCLUSION: Intoxication with MBT is a potentially life-threatening intoxication causing severe methemoglobinemia and multi-organ failure. Extracorporeal liver albumin dialysis (MARS) appears to be an effective treatment to allow recovery of hepatic function. |
format | Text |
id | pubmed-1481609 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-14816092006-06-22 Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report Braun, Claude Birck, Rainer Singer, Manfred V Schnuelle, Peter van der Woude, Fokko J Löhr, Matthias BMC Emerg Med Case Report BACKGROUND: Methylene bis(thiocyanate) (MBT) is a microbiocidal agent mainly used in industrial water cooling systems and paper mills as an inhibitor of algae, fungi, and bacteria. CASE PRESENTATION: We describe the first case of severe intoxication following inhalation of powder in an industrial worker. Profound cyanosis and respiratory failure caused by severe methemoglobinemia developed within several minutes. Despite immediate admission to the intensive care unit, where mechanical ventilation and hemodialysis for toxin elimination were initiated, multi-organ failure involving liver, kidneys, and lungs developed. While liver failure was leading, the patient was successfully treated with the MARS (molecular adsorbent recirculating system) procedure. CONCLUSION: Intoxication with MBT is a potentially life-threatening intoxication causing severe methemoglobinemia and multi-organ failure. Extracorporeal liver albumin dialysis (MARS) appears to be an effective treatment to allow recovery of hepatic function. BioMed Central 2006-04-11 /pmc/articles/PMC1481609/ /pubmed/16608508 http://dx.doi.org/10.1186/1471-227X-6-5 Text en Copyright © 2006 Braun et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Braun, Claude Birck, Rainer Singer, Manfred V Schnuelle, Peter van der Woude, Fokko J Löhr, Matthias Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report |
title | Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report |
title_full | Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report |
title_fullStr | Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report |
title_full_unstemmed | Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report |
title_short | Life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. A case report |
title_sort | life-threatening intoxication with methylene bis(thiocyanate): clinical picture and pitfalls. a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1481609/ https://www.ncbi.nlm.nih.gov/pubmed/16608508 http://dx.doi.org/10.1186/1471-227X-6-5 |
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