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A base pair at the bottom of the anticodon stem is reciprocally preferred for discrimination of cognate tRNAs by Escherichia coli lysyl- and glutaminyl-tRNA synthetases
Although the yeast amber suppressor tRNA(Tyr) is a good candidate for a carrier of unnatural amino acids into proteins, slight misacylation with lysine was found to occur in an Escherichia coli protein synthesis system. Although it was possible to restrain the mislysylation by genetically engineerin...
Autores principales: | Fukunaga, Jun-ichi, Ohno, Satoshi, Nishikawa, Kazuya, Yokogawa, Takashi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483225/ https://www.ncbi.nlm.nih.gov/pubmed/16772402 http://dx.doi.org/10.1093/nar/gkl414 |
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