Cargando…

Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers

BACKGROUND: The MDM2 gene encodes a negative regulator of the p53 tumour suppressor protein. A single nucleotide polymorphism (SNP) in the MDM2 promoter (a T to G exchange at nucleotide 309) has been reported to produce accelerated tumour formation in individuals with inherited p53 mutations. We hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Copson, Ellen R, White, Helen E, Blaydes, Jeremy P, Robinson, David O, Johnson, Peter W, Eccles, Diana M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483833/ https://www.ncbi.nlm.nih.gov/pubmed/16563154 http://dx.doi.org/10.1186/1471-2407-6-80

Ejemplares similares

Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers
por: Bjørnslett, Merete, et al.
Publicado: (2012)

MDM2 SNP309 polymorphism is associated with colorectal cancer risk
por: Wang, Weizhi, et al.
Publicado: (2014)

Correlations between MDM2 gene SNP309 Polymorphism and Susceptibility to Leukemia
por: Ou, Wen-Bin
Publicado: (2015)

Mdm2-SNP309 polymorphism in prostate cancer: no evidence for association with increased risk or histopathological tumour characteristics
por: Stoehr, R, et al.
Publicado: (2008)

Effects of the single nucleotide polymorphism at MDM2 309 on breast cancer patients with/without BRCA1/2 mutations
por: Nechushtan, Hovav, et al.
Publicado: (2009)

An Updated Meta-Analysis on the Association of MDM2 SNP309 Polymorphism with Colorectal Cancer Risk
por: Qin, Xue, et al.
Publicado: (2013)

MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer risk
por: Knappskog, Stian, et al.
Publicado: (2011)

The MDM2 Single-Nucleotide Polymorphism T309G Is Associated With the Development of Epimacular Membranes
por: Jiang, Heng, et al.
Publicado: (2022)

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism
por: Paulin, Fiona EM, et al.
Publicado: (2008)

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
por: Sinilnikova, O M, et al.
Publicado: (2009)

Prognostic Impact of the MDM2(SNP309) Allele in Leukemia and Lymphoma
por: Post, Sean M., et al.
Publicado: (2010)

MDM2 SNP309 rs2279744 Polymorphism and Gastric Cancer Risk: A Meta-Analysis
por: Ma, Yong, et al.
Publicado: (2013)

Impact of TP53 Codon 72 and MDM2 SNP 309 Polymorphisms in Pancreatic Ductal Adenocarcinoma
por: Hori, Yasuki, et al.
Publicado: (2015)

MDM2 SNP309 promoter polymorphism and p53 mutations in urinary bladder carcinoma stage T1
por: Olsson, Hans, et al.
Publicado: (2013)

MDM2 SNP309 polymorphism contributes to endometrial cancer susceptibility: evidence from a meta-analysis
por: Peng, Qiliu, et al.
Publicado: (2013)

Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer
por: YONEDA, TOMOKO, et al.
Publicado: (2013)

Correction: Impact of TP53 Codon 72 and MDM2 SNP 309 Polymorphisms in Pancreatic Ductal Adenocarcinoma
Publicado: (2015)

Single-Nucleotide Polymorphism 309T>G in the MDM2 Promoter Determines Functional Outcome After Stroke
por: Rodríguez, Cristina, et al.
Publicado: (2018)

MDM2 SNP309 polymorphism is associated with lung cancer risk in women: A meta-analysis using METAGEN
por: HE, WENWU, et al.
Publicado: (2012)

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients
por: Schmidt, Marjanka K, et al.
Publicado: (2009)

MDM2 SNP309, gene-gene interaction, and tumor susceptibility: an updated meta-analysis
por: Wan, Yan, et al.
Publicado: (2011)

Correlation between MDM2 T309G single nucleotide polymorphism and esophageal cancer susceptibility: An updated meta‐analysis
por: Yin, Lele, et al.
Publicado: (2020)

Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method
por: Enokida, Yasuaki, et al.
Publicado: (2013)

A cohort study on the association of MDM2 SNP309 with lung cancer risk in Bangladeshi population
por: Reza, Hasan Al, et al.
Publicado: (2020)

Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers
por: McCrorie, Alan D, et al.
Publicado: (2020)

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients
por: Deben, Christophe, et al.
Publicado: (2017)

Association between MDM2 SNP309 and endometrial cancer risk: A PRISMA-compliant meta-analysis
por: Zou, Xinwei, et al.
Publicado: (2018)

A case‐control study on the SNP309T → G and 40‐bp Del1518 of the MDM2 gene and a systematic review for MDM2 polymorphisms in the patients with breast cancer
por: Jalilvand, Amin, et al.
Publicado: (2020)

Prognostic potential of the MDM2 309T>G polymorphism in stage I lung adenocarcinoma
por: Enokida, Yasuaki, et al.
Publicado: (2016)

Association between MDM2 SNP309 T>G polymorphism and the risk of bladder cancer: new data in a Chinese population and an updated meta-analysis
por: Xie, Linguo, et al.
Publicado: (2015)

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene
por: Mittelstrass, Kirstin, et al.
Publicado: (2008)

Association of MDM2 SNP309 Variation with Lung Cancer Risk: Evidence from 7196 Cases and 8456 Controls
por: Zhuo, Wenlei, et al.
Publicado: (2012)

Association of PIK3CA and MDM2 SNP309 with Cervical Squamous Cell Carcinoma in a Philippine Population
por: Tantengco, Ourlad Alzeus G, et al.
Publicado: (2019)

The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy
por: Pastor-Idoate, Salvador, et al.
Publicado: (2013)

Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among non-smoking Chinese women in Singapore
por: Chua, Hui Wan, et al.
Publicado: (2010)

AB265. Association between MDM2 SNP309T>G polymorphism and the risk of bladder cancer: new data in Chinese population and an update meta-analysis
por: Xie, Linguo, et al.
Publicado: (2016)

Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer
por: Sun, Ying-Fang, et al.
Publicado: (2009)

Significant Association of the MDM2 T309G Polymorphism with Breast Cancer Risk in a Turkish Population
por: Yilmaz, Meral, et al.
Publicado: (2018)

Have the roles of two functional polymorphisms in breast cancer, R72P in P53 and MDM2-309 in MDM2, become clearer?
por: Scott, Rodney J
Publicado: (2010)

Is MDM2 SNP309 Variation a Risk Factor for Head and Neck Carcinoma?: An Updated Meta-Analysis Based on 11,552 Individuals
por: Zhuo, Xianlu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_g1ec32vfrdvk7nibigthluteof