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Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants

BACKGROUND: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible. For an effective immune prophylaxis in humans, broad coverage of different strains of SARS-CoV and control of pote...

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Autores principales:	ter Meulen, Jan, van den Brink, Edward N, Poon, Leo L. M, Marissen, Wilfred E, Leung, Cynthia S. W, Cox, Freek, Cheung, Chung Y, Bakker, Arjen Q, Bogaards, Johannes A, van Deventer, Els, Preiser, Wolfgang, Doerr, Hans Wilhelm, Chow, Vincent T, de Kruif, John, Peiris, Joseph S. M, Goudsmit, Jaap
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483912/ https://www.ncbi.nlm.nih.gov/pubmed/16796401 http://dx.doi.org/10.1371/journal.pmed.0030237

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