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Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues

BACKGROUND: In prostate cancer, normal citrate-producing glandular secretory epithelial cells undergo a metabolic transformation to malignant citrate-oxidizing cells. m-Aconitase is the critical step involved in this altered citrate metabolism that is essential to prostate malignancy. The limiting m...

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Detalles Bibliográficos
Autores principales: Singh, Keshav K, Desouki, Mohamed M, Franklin, Renty B, Costello, Leslie C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1484490/
https://www.ncbi.nlm.nih.gov/pubmed/16595004
http://dx.doi.org/10.1186/1476-4598-5-14

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