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Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues
BACKGROUND: In prostate cancer, normal citrate-producing glandular secretory epithelial cells undergo a metabolic transformation to malignant citrate-oxidizing cells. m-Aconitase is the critical step involved in this altered citrate metabolism that is essential to prostate malignancy. The limiting m...
Autores principales: | Singh, Keshav K, Desouki, Mohamed M, Franklin, Renty B, Costello, Leslie C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1484490/ https://www.ncbi.nlm.nih.gov/pubmed/16595004 http://dx.doi.org/10.1186/1476-4598-5-14 |
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