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Emergence of Protein Fold Families through Rational Design
Diverse proteins with similar structures are grouped into families of homologs and analogs, if their sequence similarity is higher or lower, respectively, than 20%–30%. It was suggested that protein homologs and analogs originate from a common ancestor and diverge in their distinct evolutionary time...
Autores principales: | Ding, Feng, Dokholyan, Nikolay V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1487181/ https://www.ncbi.nlm.nih.gov/pubmed/16839198 http://dx.doi.org/10.1371/journal.pcbi.0020085 |
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