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Production of IL-16 correlates with CD4+ Th1 inflammation and phosphorylation of axonal cytoskeleton in multiple sclerosis lesions

BACKGROUND: Multiple sclerosis (MS) is a central nervous system-specific autoimmune, demyelinating and neurodegenerative disease. Infiltration of lesions by autoaggressive, myelin-specific CD4+Th1 cells correlates with clinical manifestations of disease. The cytokine IL-16 is a CD4+ T cell-specific...

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Detalles Bibliográficos
Autores principales:	Skundric, Dusanka S, Cai, Juan, Cruikshank, William W, Gveric, Djordje
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488832/ https://www.ncbi.nlm.nih.gov/pubmed/16729885 http://dx.doi.org/10.1186/1742-2094-3-13

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