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Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics
BACKGROUND: Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing. Recently however, actively transcribed genes have also been found localized to the nuclear periphery i...
Autores principales: | Drubin, David A, Garakani, Arman M, Silver, Pamela A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488840/ https://www.ncbi.nlm.nih.gov/pubmed/16635267 http://dx.doi.org/10.1186/1471-2121-7-19 |
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