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Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models

BACKGROUND: Abdominal aortic aneurysm (AAA) is a dilatation of the aortic wall, which can rupture, if left untreated. Previous work has shown that, maximum diameter is not a reliable determinant of AAA rupture. However, it is currently the most widely accepted indicator. Wall stress may be a better...

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Autores principales: Leung, James H, Wright, Andrew R, Cheshire, Nick, Crane, Jeremy, Thom, Simon A, Hughes, Alun D, Xu, Yun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488849/
https://www.ncbi.nlm.nih.gov/pubmed/16712729
http://dx.doi.org/10.1186/1475-925X-5-33
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author Leung, James H
Wright, Andrew R
Cheshire, Nick
Crane, Jeremy
Thom, Simon A
Hughes, Alun D
Xu, Yun
author_facet Leung, James H
Wright, Andrew R
Cheshire, Nick
Crane, Jeremy
Thom, Simon A
Hughes, Alun D
Xu, Yun
author_sort Leung, James H
collection PubMed
description BACKGROUND: Abdominal aortic aneurysm (AAA) is a dilatation of the aortic wall, which can rupture, if left untreated. Previous work has shown that, maximum diameter is not a reliable determinant of AAA rupture. However, it is currently the most widely accepted indicator. Wall stress may be a better indicator and promising patient specific results from structural models using static pressure, have been published. Since flow and pressure inside AAA are non-uniform, the dynamic interaction between the pulsatile flow and wall may influence the predicted wall stress. The purpose of the present study was to compare static and dynamic wall stress analysis of patient specific AAAs. METHOD: Patient-specific AAA models were created from CT scans of three patients. Two simulations were performed on each lumen model, fluid structure interaction (FSI) model and static structural (SS) model. The AAA wall was created by dilating the lumen with a uniform 1.5 mm thickness, and was modeled as a non-linear hyperelastic material. Commercial finite element code Adina 8.2 was used for all simulations. The results were compared between the FSI and SS simulations. RESULTS: Results are presented for the wall stress patterns, wall shear stress patterns, pressure, and velocity fields within the lumen. It is demonstrated that including fluid flow can change local wall stresses slightly. However, as far as the peak wall stress is concerned, this effect is negligible as the difference between SS and FSI models is less than 1%. CONCLUSION: The results suggest that fully coupled FSI simulation, which requires considerable computational power to run, adds little to rupture risk prediction. This justifies the use of SS models in previous studies.
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spelling pubmed-14888492006-07-06 Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models Leung, James H Wright, Andrew R Cheshire, Nick Crane, Jeremy Thom, Simon A Hughes, Alun D Xu, Yun Biomed Eng Online Research BACKGROUND: Abdominal aortic aneurysm (AAA) is a dilatation of the aortic wall, which can rupture, if left untreated. Previous work has shown that, maximum diameter is not a reliable determinant of AAA rupture. However, it is currently the most widely accepted indicator. Wall stress may be a better indicator and promising patient specific results from structural models using static pressure, have been published. Since flow and pressure inside AAA are non-uniform, the dynamic interaction between the pulsatile flow and wall may influence the predicted wall stress. The purpose of the present study was to compare static and dynamic wall stress analysis of patient specific AAAs. METHOD: Patient-specific AAA models were created from CT scans of three patients. Two simulations were performed on each lumen model, fluid structure interaction (FSI) model and static structural (SS) model. The AAA wall was created by dilating the lumen with a uniform 1.5 mm thickness, and was modeled as a non-linear hyperelastic material. Commercial finite element code Adina 8.2 was used for all simulations. The results were compared between the FSI and SS simulations. RESULTS: Results are presented for the wall stress patterns, wall shear stress patterns, pressure, and velocity fields within the lumen. It is demonstrated that including fluid flow can change local wall stresses slightly. However, as far as the peak wall stress is concerned, this effect is negligible as the difference between SS and FSI models is less than 1%. CONCLUSION: The results suggest that fully coupled FSI simulation, which requires considerable computational power to run, adds little to rupture risk prediction. This justifies the use of SS models in previous studies. BioMed Central 2006-05-19 /pmc/articles/PMC1488849/ /pubmed/16712729 http://dx.doi.org/10.1186/1475-925X-5-33 Text en Copyright © 2006 Leung et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Leung, James H
Wright, Andrew R
Cheshire, Nick
Crane, Jeremy
Thom, Simon A
Hughes, Alun D
Xu, Yun
Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
title Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
title_full Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
title_fullStr Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
title_full_unstemmed Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
title_short Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
title_sort fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488849/
https://www.ncbi.nlm.nih.gov/pubmed/16712729
http://dx.doi.org/10.1186/1475-925X-5-33
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