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Secondary structure effects on DNA hybridization kinetics: a solution versus surface comparison
The hybridization kinetics for a series of designed 25mer probe–target pairs having varying degrees of secondary structure have been measured by UV absorbance and surface plasmon resonance (SPR) spectroscopy in solution and on the surface, respectively. Kinetic rate constants derived from the result...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488884/ https://www.ncbi.nlm.nih.gov/pubmed/16822858 http://dx.doi.org/10.1093/nar/gkl422 |